Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Isolated hemihyperplasia

Disease definition

Isolated hemihyperplasia is a rare overgrowth syndrome characterized by an asymmetric regional body overgrowth, involving at least one limb, and associated with an increased risk of developing embryonal tumors, principally nephroblastoma (see this term) and hepoblastoma.


  • Synonym(s):
    • Hemi 3 syndrome
    • Hemicorporal hypertrophy
    • Isolated hemihypertrophy
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: Q87.3
  • OMIM: 235000
  • UMLS: C0332890  C1856184
  • MeSH: -
  • GARD: 2630
  • MedDRA: 10019463

Additional information

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.