Orphanet: Carcinosarcoma of the corpus uteri

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Carcinosarcoma of the corpus uteri

Disease definition

Carcinosarcoma of the corpus uteri is a rare, malignant, mixed epithelial and mesenchymal tumor of the uterine body composed of high-grade carcinomatous and sarcomatous elements. It may present with vaginal bleeding, abnormal vaginal discharge, abdominal pain and/or pelvic mass, with a polypoid tumor sometimes protruding through the cervical canal. Association with Tamoxifen therapy, long-term unopposed estrogen use and previous pelvic radiotherapy has been reported.


Classification level: Disorder
  • Synonym(s):
    • Malignant mixed Müllerian tumor of the corpus uteri
    • Mixed Müllerian cancer of corpus uteri
    • Uterine carcinosarcoma
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: C54.9
  • OMIM: -
  • UMLS: -
  • MeSH: -
  • GARD: 12335
  • MedDRA: -

Detailed information

Article for general public


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.