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Malignant germ cell tumor of the cervix uteri

Disease definition

Malignant germ cell tumor of the cervix uteri is an extremely rare uterine neoplasm characterized by a usually polypoid, friable tumor deriving from primordial germ cells located in the uterine cervix. Presentation is non-specific and often includes abnormal vaginal bleeding and/or discharge, a cervical mass protruding from the vagina, abdominal and/or pelvic pain or, less commonly, difficulty passing stool and perianal pain. Various histological subtypes (incl. dysgerminoma, yolk sac tumor, choriocarcinoma and malignant teratoma) are reported.

ORPHA:213837

Classification level: Disorder
  • Synonym(s):
    • Cervical germ cell cancer
    • Cervical malignant germ cell tumor
    • Germ cell cancer of the cervix uteri
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: C53.0  C53.1  C53.8
  • OMIM: -
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -

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