Orphanet: Attenuated familial adenomatous polyposis

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Attenuated familial adenomatous polyposis

Disease definition

A mild form of familial adenomatous polyposis characterized by the presence of fewer than 100 adenomatous colonic polyps, a more proximal colonic location, a delayed age of colorectal cancer onset and a more limited expression of the extracolonic features.


Classification level: Disorder
  • Synonym(s):
    • AFAP
    • Attenuated FAP
    • Attenuated familial polyposis coli
  • Prevalence: -
  • Inheritance: Autosomal dominant or Autosomal recessive 
  • Age of onset: Adult
  • ICD-10: D12.6
  • OMIM: 175100  608456  612591  615083  616415
  • UMLS: C2674616
  • MeSH: C538265
  • GARD: 8532
  • MedDRA: -

Detailed information

General public

Disease review articles

Genetic Testing

ERN : produced/endorsed by ERN(s)
FSMR : produced/endorsed by FSMR(s)
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