Orphanet: Attenuated familial adenomatous polyposis

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Attenuated familial adenomatous polyposis

Disease definition

A mild form of familial adenomatous polyposis characterized by the presence of fewer than 100 adenomatous colonic polyps, a more proximal colonic location, a delayed age of colorectal cancer onset and a more limited expression of the extracolonic features.


Classification level: Disorder
  • Synonym(s):
    • AFAP
    • Attenuated FAP
    • Attenuated familial polyposis coli
  • Prevalence: -
  • Inheritance: Autosomal dominant or Autosomal recessive 
  • Age of onset: Adult
  • ICD-10: D12.6
  • OMIM: 175100  608456  612591  615083  616415
  • UMLS: C2674616
  • MeSH: C538265
  • GARD: 8532
  • MedDRA: -

Detailed information

Article for general public


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.