Orphanet: Hypoplastic left heart syndrome

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Hypoplastic left heart syndrome

Disease definition

A rare, congenital, non-syndromic, heart malformation characterized by under development of the left-sided cardiac structures (including left ventricle, ascending aorta, aortic arch, and mitral and/or aortic valve) such that the left heart is unable to provide adequate systemic cardiac output.


Classification level: Disorder
  • Synonym(s):
    • HLHS
  • Prevalence: Unknown
  • Inheritance: Unknown 
  • Age of onset: Neonatal, Antenatal
  • ICD-10: Q23.4
  • ICD-11: LA89.3
  • OMIM: 241550  614435
  • UMLS: C0152101
  • MeSH: D018636
  • GARD: 6739
  • MedDRA: 10021076

Detailed information

General public


Disease review articles

ERN : produced/endorsed by ERN(s)
FSMR : produced/endorsed by FSMR(s)
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