Orphanet: Acute fatty liver of pregnancy

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Acute fatty liver of pregnancy

Disease definition

A rare, severe complication occurring in the third trimester of pregnancy or in early postpartum period bearing a risk for perinatal and maternal mortality and characterized by jaundice, rise of hepatic injuries and evolving to acute liver failure and encephalopathy.


Classification level: Disorder
  • Synonym(s):
    • AFLP
  • Prevalence: -
  • Inheritance: Multigenic/multifactorial 
  • Age of onset: Adult
  • ICD-10: O26.6
  • OMIM: -
  • UMLS: C1455728
  • MeSH: C537957
  • GARD: 9578
  • MedDRA: 10000746
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