Orphanet: 3M syndrome

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

3M syndrome

Disease definition

A primordial growth disorder characterized by low birth weight, reduced birth length, severe postnatal growth restriction, a spectrum of minor anomalies (including facial dysmorphism) and normal intelligence.


Classification level: Disorder
  • Synonym(s):
    • 3-M syndrome
    • Dolichospondylic dysplasia
    • Gloomy face syndrome
    • Le Merrer syndrome
    • Yakut short stature syndrome
  • Prevalence: Unknown
  • Inheritance: Autosomal recessive 
  • Age of onset: Infancy, Neonatal
  • ICD-10: Q87.1
  • OMIM: 273750  612921  614205
  • UMLS: C1848862  C1851996  C2678312
  • MeSH: -
  • GARD: 5667
  • MedDRA: -

Detailed information


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.