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Postpoliomyelitis syndrome

Disease definition

Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis (see this term), 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing.

ORPHA:2942

Classification level: Disorder
  • Synonym(s):
    • Postpolio sequelae
    • Postpolio syndrome
    • Postpoliomyelitic syndrome
    • Postpoliomyelitis sequelae
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: Adolescent, Adult, Elderly
  • ICD-10: G14
  • ICD-11: 8B62
  • OMIM: -
  • UMLS: C0080040
  • MeSH: -
  • GARD: 4454
  • MedDRA: -

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The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.