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Chronic nonbacterial osteomyelitis/Chronic recurrent multifocal osteomyelitis

Disease definition

Chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), is a chronic autoinflammatory syndrome that is characterized by multiple foci of painful swelling of bones, mainly in the metaphyses of the long bones, in addition to the pelvis, the shoulder girdle and the spine.

ORPHA:324964

Classification level: Disorder
  • Synonym(s):
    • CNO/CRMO
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Not applicable 
  • Age of onset: Childhood, Adolescent
  • ICD-10: M86.3
  • OMIM: 259680
  • UMLS: C0410422
  • MeSH: -
  • GARD: 6108
  • MedDRA: -
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