Orphanet: Pediatric hepatocellular carcinoma

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Pediatric hepatocellular carcinoma

Disease definition

A rare, aggressive and malignant hepatic tumor arising from the hepatocytes. It develops mainly in children over 10 years of age, either in a cirrhotic background, or more commonly in a non-cirrhotic background (70% of cases).


Classification level: Disorder
  • Synonym(s):
    • Childhood-onset HCC
    • Childhood-onset hepatocellular carcinoma
    • Pediatric HCC
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: Childhood, Adolescent
  • ICD-10: C22.0
  • OMIM: 114550
  • UMLS: -
  • MeSH: -
  • GARD: 9331
  • MedDRA: -

Detailed information

Article for general public


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