Orphanet: Alexander disease type II

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Alexander disease type II

Disease definition

An astrogliopathy and a form of Alexander disease (AxD) characterized by ataxia, bulbar symptoms, spastic paraparesis, palatal myoclonus, and autonomic symptoms.


Classification level: Subtype of disorder
  • Synonym(s):
    • AxD type II
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant 
  • Age of onset: Adolescent, Childhood, Adult
  • ICD-10: E75.2
  • OMIM: 203450
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information

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