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Adiposis dolorosa

Disease definition

Adiposis dolorosa or Dercum's disease is characterised by the development of multiple, painful, subcutaneous lipomas in association with obesity, asthenia and fatigue, and range of mental disturbances including instability, depression, confusion, dementia and epilepsy.


  • Synonym(s):
    • Adiposalgia
    • Adipose tissue rheumatism
    • Dercum disease
    • Lipomatosis dolorosa
    • Neurolipomatosis
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant or Not applicable 
  • Age of onset: Adult
  • ICD-10: E88.2
  • OMIM: 103200
  • UMLS: C0001529
  • MeSH: D000274
  • GARD: 5750
  • MedDRA: 10001294

Detailed information


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