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Stevens-Johnson syndrome
Disease definition
Stevens-Johnson syndrome is a limited form of toxic epidermal necrolysis (see this term) characterized by destruction and detachment of the skin epithelium and mucous membranes involving less than 10% of the body surface area.
ORPHA:36426
Classification level: Subtype of disorderSummary
Epidemiology
The annual incidence of Stevens-Johnson syndrome is less than 1/1,000,000.
Etiology
Stevens-Johnson syndrome can be triggered by a drug allergy and, more rarely, by infections or bone marrow transplantation. In 25 to 30% of cases, the cause is unclear.
Management and treatment
Patients should be admitted to an intensive care or burns unit as soon as the diagnosis is suspected.
Prognosis
Reepithelialization is rapid (2-3 weeks).
Detailed information
Professionals
- Emergency guidelines
- Français (2012, pdf)
- Review article
- Français (2007, pdf)
- English (2010)
- Clinical practice guidelines
- Français (2017, pdf)
Additional information
Further information on this disease
Health care resources for this disease
Research activities on this disease
Specialised Social Services
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.