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Undifferentiated carcinoma with osteoclast-like giant cells of pancreas

Disease definition

A rare type of pancreatic ductal adenocarcinoma characterized by composition of non-neoplastic osteoclast-like multinucleated giant cells, a mononuclear histiocytic component, and the neoplastic cells, which vary from spindle-shaped to epithelioid and can be very large and pleomorphic. Clinical features of pancreatic ductal adenocarcinoma include abdominal pain, nausea, weight loss, jaundice, and new-onset diabetes.

ORPHA:424080

Classification level: Disorder
  • Synonym(s):
    • OGCT of pancreas
    • Osteoclastic giant cell tumor of pancreas
    • Pancreatic osteoclastic giant cell tumor
    • Pancreatic undifferentiated carcinoma with osteoclast-like giant cells
    • Undifferentiated carcinoma of pancreas with osteoclast-like giant cells
  • Prevalence: -
  • Inheritance: Not applicable 
  • Age of onset: -
  • ICD-10: C25.0  C25.1  C25.2  C25.7  C25.8
  • OMIM: -
  • UMLS: C2007059
  • MeSH: -
  • GARD: -
  • MedDRA: -

  A summary on this disease is available in Español (2023) Nederlands (2023)

Detailed information

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Guidelines

Disease review articles

ERN produced/endorsed by ERN(s)   FSMR produced/endorsed by FSMR(s)

Additional information

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The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.