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Acquired purpura fulminans

Disease definition

Purpura fulminans (PF) is a life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children that is characterized by purpuric skin lesions and disseminated intravascular coagulation. PF may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. There are two forms of PF that are classified according to triggering mechanisms: acute infectious (the most common form), and idiopathic PF.


  • Synonym(s): -
  • Prevalence: -
  • Inheritance: Not applicable 
  • Age of onset: Infancy, Neonatal
  • ICD-10: D65
  • OMIM: -
  • UMLS: C0043068  C0085650
  • MeSH: D014884  D055665
  • GARD: -
  • MedDRA: 10037556

Additional information

Further information on this disease

Specialised Social Services

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