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X-linked dystonia-parkinsonism

Disease definition

X-linked dystonia-parkinsonism (XDP) is a neurodegenerative movement disorder characterized by adult-onset parkinsonism that is frequently accompanied by focal dystonia, which becomes generalized over time, and that has a highly variable clinical course.


Classification level: Disorder
  • Synonym(s):
    • DYT3
    • Lubag
    • Lubag syndrome
    • XDP
  • Prevalence: <1 / 1 000 000
  • Inheritance: X-linked recessive or Not applicable 
  • Age of onset: Adult
  • ICD-10: G24.1
  • OMIM: 314250
  • UMLS: C1839130
  • MeSH: -
  • GARD: 10533
  • MedDRA: -

Detailed information


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