Orphanet: Large congenital melanocytic nevus

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Large congenital melanocytic nevus

Disease definition

A large, or giant, congenital melanocytic nevus (LCMN or GCMN) is a pigmented skin lesion of more than 20 cm - or 40 cm- respectively, projected adult diameter, composed of melanocytes, and presenting with an elevated risk of malignant transformation.


Classification level: Disorder
  • Synonym(s):
    • Congenital pigmented nevus
    • GMN
    • Giant congenital melanocytic nevus
    • Giant pigmented hairy nevus
    • LCMN
  • Prevalence: 1-9 / 100 000
  • Inheritance: -
  • Age of onset: Infancy, Neonatal
  • ICD-10: Q82.5
  • OMIM: 137550
  • UMLS: C1318558  C1842036
  • MeSH: -
  • GARD: 2469
  • MedDRA: 10072036

Detailed information


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.