Orphanet: Hereditary sensory and autonomic neuropathy type 4

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Hereditary sensory and autonomic neuropathy type 4

Disease definition

A rare hereditary sensory and autonomic neuropathy characterized by anhidrosis, insensitivity to pain, self-mutilating behavior and episodes of fever.


Classification level: Disorder
  • Synonym(s):
    • CIPA
    • Congenital insensitivity to pain with anhidrosis
    • HSAN4
    • Hereditary sensory and autonomic neuropathy type IV
  • Prevalence: Unknown
  • Inheritance: Autosomal recessive 
  • Age of onset: Infancy, Neonatal, Childhood
  • ICD-10: G60.8
  • OMIM: 256800
  • UMLS: C0020074
  • MeSH: -
  • GARD: 3006
  • MedDRA: -

Detailed information


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