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Scleroderma

Disease definition

Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal hardening of the skin and, sometimes, other organs. It is classified into two main forms: localized scleroderma and systemic sclerosis (SSc), the latter comprising three subsets; diffuse cutaneous SSc (dcSSc), limited cutaneous SSc (lcSSc) and limited SSc (lSSc) (see these terms).

ORPHA:801

Classification level: Group of disorders
  • Synonym(s): -
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: -
  • OMIM: -
  • UMLS: C0011644  C0852007
  • MeSH: -
  • GARD: -
  • MedDRA: 10039710
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