Orphanet: Boutonneuse fever
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Boutonneuse fever

Disease definition

A rare spotted fever rickettsiosis caused by infection with the tick-borne bacterium Rickettsia conorii, characterized by the onset of fever after an incubation period of about a week, followed by a centripetally spreading maculopapular rash, which may evolve into a petechial form. Accompanying symptoms are headaches, myalgia and/or arthralgia, among others. The typical ''tache noire'' may be observed at the site of the tick bite for several days. The disease is endemic in Africa, Southern Europe, and India.

ORPHA:83313

Classification level: Disorder
  • Synonym(s):
    • Mediterranean spotted fever
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: A77.1
  • OMIM: -
  • UMLS: C0006060
  • MeSH: D001907
  • GARD: -
  • MedDRA: 10006045
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