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Addison disease

Disease definition

A chronic and rare endocrine disorder due to autoimmune destruction of the adrenal cortex and resulting in a glucocorticoid and mineralocorticoid deficiency. Properly speaking, it designates autoimmune adrenalitis, but it is a term commonly used to describe any form of chronic primary adrenal insufficiency (CPAI).

ORPHA:85138

Classification level: Disorder
  • Synonym(s):
    • Autoimmune Addison disease
    • Autoimmune adrenalitis
    • Classic Addison disease
    • Primary Addison disease
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: E27.1
  • ICD-11: 5A74.0
  • OMIM: 103230  240200
  • UMLS: C0001403
  • MeSH: D000224
  • GARD: 5740
  • MedDRA: 10001130

Detailed information

General public

Guidelines

ERN produced/endorsed by ERN(s)   FSMR produced/endorsed by FSMR(s)
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.