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Systemic-onset juvenile idiopathic arthritis

Disease definition

A rare pediatric rheumatological disease characterized by the variable occurrence of chronic arthritis, intermittent high spiking fever, maculopapular rash during fever episodes, hepatomegaly and/or splenomegaly, lymphadenopathy, and serositis.


Classification level: Disorder
  • Synonym(s):
    • Still disease
    • Systemic-onset JIA
  • Prevalence: 1-9 / 100 000
  • Inheritance: Unknown or Multigenic/multifactorial 
  • Age of onset: Childhood
  • ICD-10: M08.2
  • ICD-11: FA24.4
  • OMIM: 604302  618795
  • UMLS: C0087031
  • MeSH: -
  • GARD: 10966
  • MedDRA: 10042061

Detailed information

General public


Disease review articles


Clinical Outcome Assessment (COA)

  • Patient-Centered Outcome Measures (PCOMs)
  • English (2023) - PROQOLIDTM
ERN produced/endorsed by ERN(s)   FSMR produced/endorsed by FSMR(s)
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.