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Granulomatosis with polyangiitis

Disease definition

A rare anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis characterized by necrotizing inflammation of small and medium vessels (capillaries, venules and arterioles), resulting in tissue ischemia.


Classification level: Disorder
  • Synonym(s):
    • GPA
  • Prevalence: 1-9 / 100 000
  • Inheritance: Not applicable 
  • Age of onset: Childhood, Adolescent, Adult, Elderly
  • ICD-10: M31.3
  • OMIM: 608710
  • UMLS: C0043092  C3495801
  • MeSH: D014890
  • GARD: 7880
  • MedDRA: 10047888
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.