Orphanet: Cryoglobulinemic vasculitis

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Cryoglobulinemic vasculitis

Disease definition

A rare immune complex-mediated vasculitis characterized by the presence of circulating cryoprecipitable immune complexes in the serum, manifesting clinically with the classical triad of purpura, weakness and arthralgia.


Classification level: Disorder
  • Synonym(s):
    • Essential cryoglobulinemia
    • Essential mixed cryoglobulinemia
    • Mixed cryoglobulinemia
    • Primary cryoglobulinemia
  • Prevalence: Unknown
  • Inheritance: -
  • Age of onset: All ages
  • ICD-10: D89.1
  • OMIM: 123550
  • UMLS: C0340992  C0343208  C0543697  C1852456
  • MeSH: -
  • GARD: 6386
  • MedDRA: 10027756

Detailed information

Article for general public


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