Orphanet: Idiopathic achalasia

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Idiopathic achalasia

Disease definition

Idiopathic achalasia (IA) is a primary esophageal motor disorder characterized by loss of esophageal peristalsis and insufficient lower esophageal sphincter (LES) relaxation in response to deglutition.


Classification level: Disorder
  • Synonym(s):
    • Achalasia cardia
    • Idiopathic achalasia of esophagus
    • Primary achalasia
  • Prevalence: 1-9 / 100 000
  • Inheritance: Autosomal recessive or Not applicable 
  • Age of onset: All ages
  • ICD-10: K22.0
  • OMIM: 200400
  • UMLS: C0014848  C0859976
  • MeSH: C536011
  • GARD: 5708
  • MedDRA: 10036669

Detailed information


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