Orphanet: Anaplastic large cell lymphoma

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Anaplastic large cell lymphoma

Disease definition

A rare and aggressive peripheral T-cell non-Hodgkin lymphoma, belonging to the group of CD30-positive lymphoproliferative disorders, which affects lymph nodes and extranodal sites. It is comprised of two sub-types, based on the expression of a protein called anaplastic lymphoma kinase (ALK): ALK positive and ALK negative ALCL.


Classification level: Disorder
  • Synonym(s):
    • ALCL
    • CD30 positive anaplastic large cell lymphoma
    • Ki-1 positive anaplastic large cell lymphoma
    • Primary systemic ALCL
    • sACL
  • Prevalence: 1-9 / 100 000
  • Inheritance: -
  • Age of onset: All ages
  • ICD-10: C84.6  C84.7
  • OMIM: -
  • UMLS: C0206180
  • MeSH: D017728
  • GARD: 3112
  • MedDRA: -

Detailed information

Article for general public


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