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Epithelial basement membrane dystrophy

Disease definition

A rare corneal dystrophy characterized by thickened, redundant sheets of basement membrane extending into the corneal epithelium, as well as intraepithelial lacunae filled with cellular debris, together presenting as a pattern of ''maps'', ''dots'', and ''fingerprints'' on slit-lamp examination. Patients may be asymptomatic or present with recurrent episodes of painful corneal erosions with variable visual impairment, typically beginning after the age of thirty. The condition is bilateral and may be inherited in an autosomal dominant manner.


Classification level: Disorder
  • Synonym(s):
    • Anterior basement membrane dystrophy
    • Cogan microcystic epithelial dystrophy
    • EBMD
    • Map-dot-fingerprint dystrophy
  • Prevalence: -
  • Inheritance: Autosomal dominant 
  • Age of onset: -
  • ICD-10: H18.5
  • ICD-11: 9A70.Y
  • OMIM: 121820
  • UMLS: C0521723
  • MeSH: C535477
  • GARD: 9732
  • MedDRA: -

Detailed information

Disease review articles

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The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.