Orphanet: Streptococcal toxic shock syndrome

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Streptococcal toxic-shock syndrome

Disease definition

Streptococcal toxic-shock syndrome (streptococcal TSS) is an acute disease mediated by the production of superantigenic toxins characterized by the sudden onset of fever and other febrile symptoms, pain, multisystem organ involvement and potentially leading to coma, shock and death due to a Streptococcus pyogenes infection.


Classification level: Subtype of disorder
  • Synonym(s):
    • Streptococcal TSS
  • Prevalence: -
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: A48.3
  • OMIM: -
  • UMLS: C0343532
  • MeSH: -
  • GARD: -
  • MedDRA: 10044251
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