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O'Sullivan-McLeod syndrome

Disease definition

O' Sullivan McLeod syndrome is a benign lower motor neuron disorder and a rare variant of monomelic amyotrophy (MA; see this term), characterized by an initial unilateral weakness in the intrinsic hand muscles that eventually spreads to the opposite limb (with an asymmetrical distribution) and that has a very slow progression of muscular atrophy over a 20 year period.


  • Synonym(s): -
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: G12.8
  • OMIM: -
  • UMLS: C2721741
  • MeSH: -
  • GARD: -
  • MedDRA: 10069682

Detailed information


Additional information

Further information on this disease

Specialised Social Services

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