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Early-onset cerebellar ataxia with retained tendon reflexes

Disease definition

Early onset cerebellar ataxia with retained reflexes (EOCARR) or Harding ataxia is a cerebellar ataxia characterized by the progressive association of a cerebellar and pyramidal syndrome with progressive cerebellar ataxia, brisk tendon reflexes, and sometimes profound sensory loss.


Classification level: Disorder
  • Synonym(s):
    • EOCA
    • EOCARR
    • Harding ataxia
  • Prevalence: 1-9 / 100 000
  • Inheritance: Autosomal recessive 
  • Age of onset: Childhood, Adolescent, Adult
  • ICD-10: G11.1
  • OMIM: 212895
  • UMLS: C0393520
  • MeSH: C535633
  • GARD: 2600
  • MedDRA: -

Detailed information


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