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RET - ret proto-oncogene
- Synonym(s) : cadherin-related family member 16, CDHF12, CDHR16, PTC, rearranged during transfection, RET51, RET receptor tyrosine kinase
- Previous symbols and names : HSCR1, Hirschsprung disease 1, MEN2A, MEN2B, MTC1, multiple endocrine neoplasia and medullary thyroid carcinoma 1
- Type : gene with protein product
- Chromosomal location : 10q11.21
- OMIM: 164761
- HGNC: 9967
- UniProtKB: P07949
- Genatlas: RET
- GenCC: RET
- Ensembl: ENSG00000165731
- IUPHAR-DB: 2185
- Reactome: P07949
- LOVD: RET
Diseases list
- Disease-causing germline mutation(s) in Familial medullary thyroid carcinoma
ORPHA:99361 
- Disease-causing germline mutation(s) in Haddad syndrome
ORPHA:99803 - Disease-causing germline mutation(s) in Hirschsprung disease
ORPHA:388 - Disease-causing germline mutation(s) in Multiple endocrine neoplasia type 2A
ORPHA:247698 - Disease-causing germline mutation(s) in Multiple endocrine neoplasia type 2B
ORPHA:247709 - Disease-causing germline mutation(s) in Renal agenesis, unilateral
ORPHA:93100 - Disease-causing germline mutation(s) (loss of function) in Renal agenesis, bilateral
ORPHA:1848 - Part of a fusion gene in Differentiated thyroid carcinoma
ORPHA:146 - Major susceptibility factor in Sporadic pheochromocytoma/secreting paraganglioma
ORPHA:276621 - Candidate gene tested in Hereditary pheochromocytoma-paraganglioma
ORPHA:29072 - Candidate gene tested in Selection of therapeutic option in non-small cell lung carcinoma
ORPHA:357191
: AssessedAdditional information
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