Search for a gene
BCR - BCR activator of RhoGEF and GTPase
- Synonym(s) : ALL, CML, D22S662, PHL
- Previous symbols and names : BCR, RhoGEF and GTPase activating protein, BCR1, D22S11, breakpoint cluster region
- Type : gene with protein product
- Chromosomal location : 22q11.23
- OMIM: 151410
- HGNC: 1014
- UniProtKB: P11274
- Genatlas: BCR
- GenCC: BCR
- Ensembl: ENSG00000186716
- IUPHAR-DB: 2755
- Reactome: P11274
- LOVD: BCR
Diseases list
- Part of a fusion gene in B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)
ORPHA:585909 
- Part of a fusion gene in Chronic myeloid leukemia
ORPHA:521 - Part of a fusion gene in Precursor T-cell acute lymphoblastic leukemia
ORPHA:99861 - Role in the phenotype of Distal 22q11.2 microdeletion syndrome
ORPHA:261330
: AssessedAdditional information
Patient-centred resources for this gene
Research activities on this gene
Specialised Social Services
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.
Orphanet is part of the Gene Curation Coalition, a global effort to harmonise gene-level resources.