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MPL - MPL proto-oncogene, thrombopoietin receptor
- Synonym(s) : CD110, THPOR, TPOR
- Previous symbols and names : myeloproliferative leukemia virus oncogene
- Type : gene with protein product
- Chromosomal location : 1p34.2
- OMIM: 159530
- HGNC: 7217
- UniProtKB: P40238
- Genatlas: MPL
- GenCC: MPL
- Ensembl: ENSG00000117400
- IUPHAR-DB: 1722
- Reactome: P40238
- LOVD: MPL
Diseases list
- Disease-causing germline mutation(s) in Familial thrombocytosis
ORPHA:71493 
- Disease-causing germline mutation(s) (loss of function) in Congenital amegakaryocytic thrombocytopenia
ORPHA:3319 - Disease-causing germline mutation(s) (loss of function) in Hereditary isolated aplastic anemia
ORPHA:397692 - Disease-causing somatic mutation(s) in Essential thrombocythemia
ORPHA:3318 - Disease-causing somatic mutation(s) in Polycythemia vera
ORPHA:729 - Disease-causing somatic mutation(s) in Primary myelofibrosis
ORPHA:824
: AssessedAdditional information
Patient-centred resources for this gene
Research activities on this gene
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