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Lemierre syndrome

Disease definition

Lemierre syndrome is a rare, potentially lethal, oropharyngeal infectious disease occurring in immunocompetent adolescents and young adults that is mainly due to Fusobacterium necrophorum and that is characterized by septic thrombophlebitis of the internal jugular vein that leads to septic, usually pulmonary, embolism, associated with ENT (ear, nose, and throat) infection that manifests with fever, neck pain, and tonsillopharyngitis.

ORPHA:137839

Classification level: Disorder
  • Synonym(s):
    • Lemierre postanginal sepsis
    • Postanginal sepsis secondary to orophyngeal infection
    • Septic phlebitis of the internal jugular vein
  • Prevalence: Unknown
  • Inheritance: -
  • Age of onset: Adolescent
  • ICD-10: J03.8
  • OMIM: -
  • UMLS: C0343525
  • MeSH: D057831
  • GARD: 6882
  • MedDRA: 10065552
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