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STAT3 - signal transducer and activator of transcription 3
- Synonym(s) : APRF
- Previous symbols and names : signal transducer and activator of transcription 3 (acute-phase response factor)
- Type : gene with protein product
- Chromosomal location : 17q21.2
- OMIM: 102582
- HGNC: 11364
- UniProtKB: P40763
- Genatlas: STAT3
- GenCC: STAT3
- Ensembl: ENSG00000168610
- IUPHAR-DB: 2994
- Reactome: P40763
- LOVD: STAT3
Diseases list
- Disease-causing germline mutation(s) in Autosomal dominant hyper-IgE syndrome
ORPHA:2314 
- Disease-causing germline mutation(s) in Chronic lymphoproliferative disorder of natural killer cells
ORPHA:512017 - Disease-causing germline mutation(s) (gain of function) in Isolated permanent neonatal diabetes mellitus
ORPHA:99885 - Disease-causing germline mutation(s) (gain of function) in STAT3-related early-onset multisystem autoimmune disease
ORPHA:438159 - Disease-causing somatic mutation(s) in T-cell large granular lymphocyte leukemia
ORPHA:86872 - Part of a fusion gene in Acute promyelocytic leukemia
ORPHA:520
: AssessedAdditional information
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