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Necrobiotic xanthogranuloma

Disease definition

Necrobiotic xanthogranuloma is a rare, chronic and progressive, non-Langerhans cell histiocytosis disease typically characterized by multiple, indurated, asymptomatic to pruritic, yellow-orange plaques or nodules that tend to ulcerate and are usually located in the periorbital area, trunk and/or extremities. Strong association with paraproteinemia and/or malignant lymphoproliferative disease has been reported.


  • Synonym(s): -
  • Prevalence: -
  • Inheritance: Not applicable 
  • Age of onset: -
  • ICD-10: D76.3
  • OMIM: -
  • UMLS: C1275339
  • MeSH: D058252
  • GARD: 10951
  • MedDRA: -

Additional information

Further information on this disease

Specialised Social Services

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