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Castleman disease

Disease definition

A benign lymphoproliferative disorder that may present as a localized or multicentric form. The clinical manifestations are heterogeneous, ranging from asymptomatic discrete lymphadenopathy to recurrent episodes of diffuse lymphadenopathy with severe systemic symptoms.

ORPHA:160

Classification level: Disorder
  • Synonym(s):
    • Angiofollicular ganglionic hyperplasia
    • Angiofollicular lymph hyperplasia
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: D47.7
  • ICD-11: 4B2Y
  • OMIM: 148000
  • UMLS: C0017531
  • MeSH: C536362  D005871
  • GARD: 12656
  • MedDRA: 10050251

Detailed information

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The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.