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Childhood disintegrative disorder

Disease definition

Childhood disintergrative disorder is a rare pervasive developmental disorder with a disease onset before the age of three and characterized by a dramatic loss of behavioral and developmental functioning after atleast two years of normal development. Manifestations of the disease include loss of speech, incontinence, communication and social interaction problems, stereotypical autistic behaviors and dementia.


Classification level: Disorder
  • Synonym(s):
    • Dementia infantilis
    • Heller syndrome
  • Prevalence: 1-9 / 100 000
  • Inheritance: Not applicable 
  • Age of onset: Childhood
  • ICD-10: F84.3
  • ICD-11: 6A02.3
  • OMIM: -
  • UMLS: C0236791
  • MeSH: -
  • GARD: 6040
  • MedDRA: 10008522

Detailed information


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