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Moderate hemophilia A

Disease definition

A moderately severe form of hemophilia A characterized by factor VIII deficiency (biological activity between 1 and 5 IU/dL) leading to abnormal bleeding as a result of minor injuries, or following trauma, surgery or tooth extraction. Spontaneous hemorrhages are rare. The condition primarily affects males but may also be observed in female carriers of disease-causing mutations.


Classification level: Subtype of disorder
  • Synonym(s):
    • Moderate congenital F8 deficiency
    • Moderate congenital factor VIII deficiency
  • Prevalence: -
  • Inheritance: X-linked recessive 
  • Age of onset: Infancy, Neonatal
  • ICD-10: D66
  • OMIM: 306700
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information

Article for general public

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