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Cerebral autosomal recessive arteriopathy-subcortical infarcts-leukoencephalopathy

Disease definition

CARASIL is a hereditary cerebral small vessel disease characterized by early-onset gait disturbances, premature scalp alopecia, ischemic stroke, acute mid to lower back pain and progressive cognitive disturbances leading to severe dementia.


Classification level: Disorder
  • Synonym(s):
    • Maeda syndrome
  • Prevalence: Unknown
  • Inheritance: Autosomal recessive 
  • Age of onset: Adolescent, Adult
  • ICD-10: I67.8
  • ICD-11: 8B22.C1
  • OMIM: 600142
  • UMLS: C1838577
  • MeSH: -
  • GARD: 10424
  • MedDRA: -

Detailed information


Disease review articles

ERN : produced/endorsed by ERN(s)
FSMR : produced/endorsed by FSMR(s)
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.