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Carcinosarcoma of the corpus uteri

Disease definition

Carcinosarcoma of the corpus uteri is a rare, malignant, mixed epithelial and mesenchymal tumor of the uterine body composed of high-grade carcinomatous and sarcomatous elements. It may present with vaginal bleeding, abnormal vaginal discharge, abdominal pain and/or pelvic mass, with a polypoid tumor sometimes protruding through the cervical canal. Association with Tamoxifen therapy, long-term unopposed estrogen use and previous pelvic radiotherapy has been reported.


Classification level: Disorder
  • Synonym(s):
    • Malignant mixed Müllerian tumor of the corpus uteri
    • Mixed Müllerian cancer of corpus uteri
    • Uterine carcinosarcoma
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: C54.9
  • ICD-11: 2C76.43
  • OMIM: -
  • UMLS: C1704376
  • MeSH: -
  • GARD: 12335
  • MedDRA: -

Detailed information

General public

ERN produced/endorsed by ERN(s)   FSMR produced/endorsed by FSMR(s)
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