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Marchiafava-Bignami disease
Disease definition
A rare neurologic disease most prominently characterized by progressive demyelination and necrosis of the corpus callosum. It is in most cases associated with chronic alcoholism and malnutrition. Speed of onset and clinical presentation are very variable with a range of possible symptoms, including dementia, seizures, gait abnormalities, dysarthria, aphasia, athetosis, as well as stupor and coma.
ORPHA:221074
Classification level: DisorderA summary on this disease is available in Deutsch (2020) Español (2020) Français (2020) Italiano (2020) Nederlands (2020)
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