Orphanet: Megacystis microcolon intestinal hypoperistalsis syndrome

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Megacystis-microcolon-intestinal hypoperistalsis syndrome

Disease definition

Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare congenital disease characterized by massive abdominal distension caused by a largely dilated non-obstructed urinary bladder (megacystis), microcolon and decreased or absent intestinal peristalsis.


Classification level: Disorder
  • Synonym(s):
    • Berdon syndrome
    • MMIHS
    • Megacystis-microcolon-intestinal hypoperistalsis-hydronephrosis syndrome
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant or Autosomal recessive 
  • Age of onset: Infancy, Neonatal
  • ICD-10: Q43.8
  • OMIM: 249210
  • UMLS: C1608393
  • MeSH: -
  • GARD: 3442
  • MedDRA: -
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