Orphanet: HELLP syndrome

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HELLP syndrome

Disease definition

A rare hemorrhagic disorder due to an acquired platelet anomaly characterized by hemolysis, elevated liver enzymes and thrombocytopenia that affects pregnant or post-partum women, and is frequently associated with severe preeclampsia. Symptoms are variable, typically including right upper quadrant or epigastric abdominal pain, nausea, vomiting, excessive weight gain, generalized edema, hypertension, general malaise, right shoulder pain, backache, and/or headache. Hepatic hemorrhage and rupture, renal failure, and pulmonary edema can result in maternal and/or fetal death.

ORPHA:244242

Classification level: Disorder

Synonym(s):
- Hemolysis, elevated liver enzymes, low platelets in pregnancy
- Hemolysis-elevated liver enzymes-low platelets syndrome
Prevalence: Unknown
Inheritance: Multigenic/multifactorial
Age of onset: Adult
ICD-10: O14.2
ICD-11: JA24.2
OMIM: -
UMLS: C0162739
MeSH: D017359
GARD: 8528
MedDRA: 10049058

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HELLP syndrome

ORPHA:244242

A summary on this disease is available in Deutsch (2019) Español (2019) Français (2019) Italiano (2019) Nederlands (2019)

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