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Inhalational anthrax

Disease definition

Inhalational anthrax is a rare acute systemic infection caused by the inhalation of Bacillus anthracis spores (e.g. through infected animal products, bioterrorism) and characterized by an initial stage where patients present with non specific symptoms (fever, cough, chills, fatigue) that is followed by an acute phase during which hemorrhagic mediastinitis occurs that can progress into meningitis, gastrointestinal involvement, and refractory shock, that can be fatal, if left untreated.

ORPHA:247257

Classification level: Disorder
  • Synonym(s):
    • Inhalation anthrax disease
    • Pulmonary anthrax
    • Respiratory anthrax
    • Respiratory anthrax disease
  • Prevalence: <1 / 1 000 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: A22.1
  • ICD-11: 1B97
  • OMIM: -
  • UMLS: C0155866
  • MeSH: -
  • GARD: -
  • MedDRA: 10035667
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