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Ménétrier disease

Disease definition

Ménétrier disease (MD) is a rare premalignant hyperproliferative gastropathy characterized by massive overgrowth of foveolar cells in the gastric lining, resulting in large gastric folds, and manifesting with epigastric pain, nausea, vomiting, peripheral edema and, less commonly, anorexia and weight loss.


Classification level: Disorder
  • Synonym(s):
    • Giant hypertrophic gastritis
    • Hypoproteinemic hypertrophic gastropathy
  • Prevalence: Unknown
  • Inheritance: Unknown or Not applicable or Autosomal dominant 
  • Age of onset: Childhood, Adolescent, Adult
  • ICD-10: K29.6
  • OMIM: 137280
  • UMLS: C0017155  C2936660
  • MeSH: -
  • GARD: 2436
  • MedDRA: 10017807  10017868
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