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Anaplastic astrocytoma
Disease definition
A rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord.
ORPHA:251589
Classification level: DisorderA summary on this disease is available in Italiano (2019) Deutsch (2017) Español (2017) Français (2017) Nederlands (2017)
Detailed information
Guidelines
- Clinical practice guidelines
- English (2011, pdf) - BNOS
: produced/endorsed by ERN(s)
: produced/endorsed by FSMR(s)Additional information
Further information on this disease
Patient-centred resources for this disease
Research activities on this disease
Specialised Social Services
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