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Diffuse astrocytoma

Disease definition

A rare low-grade astrocytoma characterized by a high degree of cellular differentiation, slow growth, and diffuse infiltration of adjacent brain structures, and corresponding to WHO grade II. The tumor typically affects young adults and has an intrinsic tendency for progression to high-grade glioma. Histological variants are fibrillary, gemistocytic, and protoplasmic astrocytoma. Patients most commonly present with seizures, but also with other neurological or neuropsychological abnormalities, depending on the location.


Classification level: Disorder
  • Synonym(s): -
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: C71.9
  • ICD-11: 2A00.0Y  XH2C49  XH2HK4  XH6UY7  XH8W32
  • OMIM: -
  • UMLS: C0280785
  • MeSH: -
  • GARD: 5907
  • MedDRA: -
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