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Early-onset generalized limb-onset dystonia

Disease definition

A rare movement disorder characterized by involuntary, repetitive, sustained muscle contractions or postures that typically begins in a single limb and, in most individuals, followed by progressive involvement of other limbs and the trunk, typically sparing the cranial and cervical region.


Classification level: Disorder
  • Synonym(s):
    • Dystonia musculorum deformans
    • EOTD
    • Early-onset generalized torsion dystonia
    • Early-onset isolated dystonia
    • Early-onset primary dystonia
    • Early-onset torsion dystonia
    • Idiopathic torsion dystonia
    • Oppenheim dystonia
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Adolescent, Childhood, Adult
  • ICD-10: G24.1
  • ICD-11: 8A02.0Y
  • OMIM: 128100  602554
  • UMLS: C0013423
  • MeSH: -
  • GARD: 2027
  • MedDRA: -

Detailed information


Disease review articles

ERN : produced/endorsed by ERN(s)
FSMR : produced/endorsed by FSMR(s)
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.