x

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.

Attention

Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Orphanet doesn't provide personalised answers. To get in touch with the Orphanet team, please contact

Information provided in your contribution (including your email address) will be stocked in .CSV files that will be sent as an email to Orphanet's teams. These emails might be conserved in the teams' mailboxes, in our backoffice servers but will not be registered in our databases (for more information see our section General Data Protection Regulation and data privacy (GDPR) and Confidentiality).

Captcha image

Early-onset generalized limb-onset dystonia

Disease definition

A rare movement disorder characterized by involuntary, repetitive, sustained muscle contractions or postures that typically begins in a single limb and, in most individuals, followed by progressive involvement of other limbs and the trunk, typically sparing the cranial and cervical region.

ORPHA:256

Classification level: Disorder
  • Synonym(s):
    • Dystonia musculorum deformans
    • EOTD
    • Early-onset generalized torsion dystonia
    • Early-onset isolated dystonia
    • Early-onset primary dystonia
    • Early-onset torsion dystonia
    • Idiopathic torsion dystonia
    • Oppenheim dystonia
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Adolescent, Childhood, Adult
  • ICD-10: G24.1
  • OMIM: 128100  602554
  • UMLS: C0013423  C1851945  C3888090
  • MeSH: -
  • GARD: 2027
  • MedDRA: -

Detailed information

Professionals

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.