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Disease definition

Osteomesopyknosis is a very rare benign bone disorder characterized by bone dysplasia manifested by patchy sclerosis of the axial skeleton and increased bone mineral content.


  • Synonym(s):
    • Axial osteosclerosis
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Childhood, Adolescent, Adult
  • ICD-10: Q78.2
  • OMIM: 166450
  • UMLS: C0432264
  • MeSH: -
  • GARD: 391
  • MedDRA: -

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